Bone Tumors and their Treatments

Patient, Caregiver, and Nurse Preferences for Treatments for Bone Metastases from Solid Tumors

BACKGROUND Bone-targeted agents (BTAs) used for the prevention of skeletal-related events (SREs) associated with metastatic bone disease possess different attributes that factor into treatment decisions. OBJECTIVE The aim of this study was to evaluate preferences of patients, caregivers, and nurses for features of BTAs used to prevent SREs in patients with a self-reported physician diagnosis ...

Treatments of Common Brain Tumors

World Health Organization (WHO) published an updated article regarding the classification of tumors of the brain. In this updated classification, brains tumors are not only classified based on their histology but molecular parameters are also incorporated in its classification. In this manuscript, we primarily focus on astrocytoma, meningioma, metastatic tumors, and pituitary tumors, providing ...

Bone Tumors

Clinical Outcomes of Surgical Treatments for Primary Malignant Bone Tumors Arising in the Acetabulum

The functional and oncologic results of eighteen patients with primary malignant periacetabular tumors were reviewed to determine the impact of surgical treatment. The reconstruction procedures were endoprosthesis (11), hip transposition (4), iliofemoral arthrodesis (2), and frozen bone autograft (1). After a mean follow-up of 62 months, 13 patients were alive and 5 had died of their disease; t...

Tumors and their stroma

As one of the most intensively studied transcription factors, it is unsurprising that p53 is involved in many biological processes, including cell cycle arrest, DNA repair, senescence and apoptosis.1 its activities are mainly regulated by posttranslational modifications and interactions with other cellular components. Over the past few years, p53 has also been linked to redox homeostasis, the b...